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BMCBI
2008
127views more  BMCBI 2008»
15 years 6 months ago
MetaMine - A tool to detect and analyse gene patterns in their environmental context
Background: Modern sequencing technologies allow rapid sequencing and bioinformatic analysis of genomes and metagenomes. With every new sequencing project a vast number of new pro...
Uta Bohnebeck, Thierry Lombardot, Renzo Kottmann, ...
BMCBI
2008
167views more  BMCBI 2008»
15 years 6 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2008
108views more  BMCBI 2008»
15 years 6 months ago
An analysis of the positional distribution of DNA motifs in promoter regions and its biological relevance
Background: Motif finding algorithms have developed in their ability to use computationally efficient methods to detect patterns in biological sequences. However the posterior cla...
Ana C. Casimiro, Susana Vinga, Ana T. Freitas, Arl...
BMCBI
2008
123views more  BMCBI 2008»
15 years 6 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
BMCBI
2008
96views more  BMCBI 2008»
15 years 6 months ago
Mapping proteins to disease terminologies: from UniProt to MeSH
Background: Although the UniProt KnowledgeBase is not a medical-oriented database, it contains information on more than 2,000 human proteins involved in pathologies. However, thes...
Anaïs Mottaz, Yum Lina Yip, Patrick Ruch, Ann...
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