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179
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BMCBI
2010
15 years 6 months ago
2010
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
189
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BMCBI
2010
15 years 6 months ago
2010
Background: An important objective of DNA microarray-based gene expression experimentation is determining interrelationships that exist between differentially expressed genes and ...
151
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BMCBI
2010
15 years 6 months ago
2010
Background: High-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to a...
184
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BMCBI
2010
15 years 6 months ago
2010
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
170
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BMCBI
2010
15 years 6 months ago
2010
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...