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BIOINFORMATICS
2006
134views more  BIOINFORMATICS 2006»
15 years 6 months ago
HaptenDB: a comprehensive database of haptens, carrier proteins and anti-hapten antibodies
The key requirement for successful immunochemical assay is the availability of antibodies with high specificity and desired affinity. Small molecules, when used as haptens, are no...
Mahender Kumar Singh, Shilpy Srivastava, G. P. S. ...
BMCBI
2006
155views more  BMCBI 2006»
15 years 6 months ago
A powerful method for detecting differentially expressed genes from GeneChip arrays that does not require replicates
Background: Studies of differential expression that use Affymetrix GeneChip arrays are often carried out with a limited number of replicates. Reasons for this include financial co...
Anne-Mette K. Hein, Sylvia Richardson
BMCBI
2006
135views more  BMCBI 2006»
15 years 6 months ago
Correcting ligands, metabolites, and pathways
Background: A wide range of research areas in bioinformatics, molecular biology and medicinal chemistry require precise chemical structure information about molecules and reaction...
Martin A. Ott, Gert Vriend
BMCBI
2006
182views more  BMCBI 2006»
15 years 6 months ago
AceTree: a tool for visual analysis of Caenorhabditis elegans embryogenesis
Background: The invariant lineage of the nematode Caenorhabditis elegans has potential as a powerful tool for the description of mutant phenotypes and gene expression patterns. We...
Thomas J. Boyle, Zhirong Bao, John I. Murray, Carl...
BMCBI
2006
144views more  BMCBI 2006»
15 years 6 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
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