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BMCBI
2007
103views more  BMCBI 2007»
15 years 6 months ago
Systems biology approach for mapping the response of human urothelial cells to infection by Enterococcus faecalis
Background: To better understand the response of urinary epithelial (urothelial) cells to Enterococcus faecalis, a uropathogen that exhibits resistance to multiple antibiotics, a ...
Mikhail G. Dozmorov, Kimberly D. Kyker, Ricardo Sa...
BMCBI
2007
122views more  BMCBI 2007»
15 years 6 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2007
167views more  BMCBI 2007»
15 years 6 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk
BMCBI
2007
154views more  BMCBI 2007»
15 years 6 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
BMCBI
2007
141views more  BMCBI 2007»
15 years 6 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
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