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168
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BMCBI
2006
15 years 6 months ago
2006
Background: DNA microarray technology provides a powerful tool for characterizing gene expression on a genome scale. While the technology has been widely used in discovery-based m...
187
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BMCBI
2006
15 years 6 months ago
2006
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
185
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BMCBI
2006
15 years 6 months ago
2006
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
186
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BMCBI
2006
15 years 6 months ago
2006
Background: Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many pr...
181
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BMCBI
2006
15 years 6 months ago
2006
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...