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199
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BMCBI
2006
15 years 6 months ago
2006
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
167
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BMCBI
2006
15 years 6 months ago
2006
Background: The Tissue Microarray (TMA) facilitates high-throughput analysis of hundreds of tissue specimens simultaneously. However, bottlenecks in the storage and manipulation o...
137
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BMCBI
2006
15 years 6 months ago
2006
Background: Molecular maps have been developed for many species, and are of particular importance for varietal development and comparative genomics. However, despite the existence...
178
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BMCBI
2006
15 years 6 months ago
2006
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
199
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BMCBI
2006
15 years 6 months ago
2006
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...