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BMCBI
2007
99views more  BMCBI 2007»
15 years 6 months ago
Statistical significance of cis-regulatory modules
Background: It is becoming increasingly important for researchers to be able to scan through large genomic regions for transcription factor binding sites or clusters of binding si...
Dustin E. Schones, Andrew D. Smith, Michael Q. Zha...
BMCBI
2007
123views more  BMCBI 2007»
15 years 6 months ago
Tracembler - software for in-silico chromosome walking in unassembled genomes
Background: Whole genome shotgun sequencing produces increasingly higher coverage of a genome with random sequence reads. Progressive whole genome assembly and eventual finishing ...
Qunfeng Dong, Matthew D. Wilkerson, Volker Brendel
BMCBI
2007
86views more  BMCBI 2007»
15 years 6 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...
BMCBI
2007
99views more  BMCBI 2007»
15 years 6 months ago
The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
B. D. Pascal, M. J. Chalmers, S. A. Busby, C. C. M...
BMCBI
2007
117views more  BMCBI 2007»
15 years 6 months ago
Application of a correlation correction factor in a microarray cross-platform reproducibility study
Background: Recent research examining cross-platform correlation of gene expression intensities has yielded mixed results. In this study, we demonstrate use of a correction factor...
Kellie J. Archer, Catherine I. Dumur, G. Scott Tay...
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