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173
Voted
BMCBI
2010
15 years 6 months ago
2010
Background: OFFGEL isoelectric focussing (IEF) has become a popular tool in proteomics to fractionate peptides or proteins. As a consequence there is a need for software solutions...
145
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BMCBI
2008
15 years 6 months ago
2008
Background: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the s...
167
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BMCBI
2007
15 years 6 months ago
2007
Background: When aligning several hundreds or thousands of sequences, such as epidemic virus sequences or homologous/orthologous sequences of some big gene families, to reconstruc...
154
Voted
BMCBI
2007
2007
Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
15 years 6 months ago
Background: There are mechanisms, notably ozone degradation, that can damage a single channel of two-channel microarray experiments. Resulting analyses therefore often choose betw...
176
Voted
BMCBI
2010
15 years 6 months ago
2010
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...