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BMCBI
2010
141views more  BMCBI 2010»
15 years 6 months ago
CIG-DB: the database for human or mouse immunoglobulin and T cell receptor genes available for cancer studies
Background: Immunoglobulin (IG or antibody) and the T-cell receptor (TR) are pivotal proteins in the immune system of higher organisms. In cancer immunotherapy, the immune respons...
Yoji Nakamura, Tomoyoshi Komiyama, Motoki Furue, T...
BMCBI
2008
107views more  BMCBI 2008»
15 years 6 months ago
A machine learning approach to explore the spectra intensity pattern of peptides using tandem mass spectrometry data
Background: A better understanding of the mechanisms involved in gas-phase fragmentation of peptides is essential for the development of more reliable algorithms for high-throughp...
Cong Zhou, Lucas D. Bowler, Jianfeng Feng
BMCBI
2010
159views more  BMCBI 2010»
15 years 6 months ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
BMCBI
2008
133views more  BMCBI 2008»
15 years 6 months ago
ElliPro: a new structure-based tool for the prediction of antibody epitopes
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...
BMCBI
2007
182views more  BMCBI 2007»
15 years 6 months ago
EDISA: extracting biclusters from multiple time-series of gene expression profiles
Background: Cells dynamically adapt their gene expression patterns in response to various stimuli. This response is orchestrated into a number of gene expression modules consistin...
Jochen Supper, Martin Strauch, Dierk Wanke, Klaus ...
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