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BMCBI
2010
125views more  BMCBI 2010»
15 years 6 months ago
A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins
Background: Several bioinformatic approaches have previously been used to find novel sites of ADAR mediated A-to-I RNA editing in human. These studies have discovered thousands of...
Mats Ensterö, Örjan Åkerborg, Dani...
BMCBI
2010
151views more  BMCBI 2010»
15 years 6 months ago
BABAR: an R package to simplify the normalisation of common reference design microarray-based transcriptomic datasets
Background: The development of DNA microarrays has facilitated the generation of hundreds of thousands of transcriptomic datasets. The use of a common reference microarray design ...
Mark J. Alston, John Seers, Jay C. D. Hinton, Sach...
BMCBI
2010
161views more  BMCBI 2010»
15 years 6 months ago
GeneMesh: a web-based microarray analysis tool for relating differentially expressed genes to MeSH terms
Background: An important objective of DNA microarray-based gene expression experimentation is determining interrelationships that exist between differentially expressed genes and ...
Saurin D. Jani, Gary L. Argraves, Jeremy L. Barth,...
BMCBI
2010
116views more  BMCBI 2010»
15 years 6 months ago
permGPU: Using graphics processing units in RNA microarray association studies
Background: Many analyses of microarray association studies involve permutation, bootstrap resampling and crossvalidation, that are ideally formulated as embarrassingly parallel c...
Ivo D. Shterev, Sin-Ho Jung, Stephen L. George, Ko...
BMCBI
2010
150views more  BMCBI 2010»
15 years 6 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
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