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» Current approaches to gene regulatory network modelling
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BMCBI
2005
178views more  BMCBI 2005»
15 years 6 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
EUROGP
2010
Springer
217views Optimization» more  EUROGP 2010»
16 years 17 days ago
Evolving Genes to Balance a Pole
We discuss how to use a Genetic Regulatory Network as an evolutionary representation to solve a typical GP reinforcement problem, the pole balancing. The network is a modified ver...
Miguel Nicolau, Marc Schoenauer, Wolfgang Banzhaf
EJASP
2010
132views more  EJASP 2010»
15 years 28 days ago
Uncovering Transcriptional Regulatory Networks by Sparse Bayesian Factor Model
The problem of uncovering transcriptional regulation by transcription factors (TFs) based on microarray data is considered. A novel Bayesian sparse correlated rectified factor mod...
Jia Meng, Jianqiu Zhang, Yuan (Alan) Qi, Yidong Ch...
TSMC
2010
15 years 23 days ago
On Robust Stability of Stochastic Genetic Regulatory Networks With Time Delays: A Delay Fractioning Approach
Robust stability serves as an important regulation mechanism in system biology and synthetic biology. In this paper, the robust stability analysis problem is investigated for a cla...
Yao Wang, Zidong Wang, Jinling Liang
BMCBI
2010
167views more  BMCBI 2010»
15 years 6 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...