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» Creating a Knowledge Base of Biological Research Papers
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RECOMB
2008
Springer
16 years 6 months ago
BayCis: A Bayesian Hierarchical HMM for Cis-Regulatory Module Decoding in Metazoan Genomes
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
Tien-ho Lin, Pradipta Ray, Geir Kjetil Sandve, Sel...
RECOMB
2006
Springer
16 years 6 months ago
Simulating Protein Motions with Rigidity Analysis
Abstract. Protein motions, ranging from molecular flexibility to largescale conformational change, play an essential role in many biochemical processes. Despite the explosion in ou...
Shawna L. Thomas, Xinyu Tang, Lydia Tapia, Nancy M...
AIEDAM
2002
100views more  AIEDAM 2002»
15 years 6 months ago
Drawing marks, acts, and reacts: Toward a computational sketching interface for architectural design
Architects use sketching and diagramming in their design process to perform functional reasoning, formal arrangements, analogy transfer, structure mapping, and knowledge acquisiti...
Ellen Yi-Luen Do
BMCBI
2008
122views more  BMCBI 2008»
15 years 6 months ago
A practical comparison of two K-Means clustering algorithms
Background: Data clustering is a powerful technique for identifying data with similar characteristics, such as genes with similar expression patterns. However, not all implementat...
Gregory A. Wilkin, Xiuzhen Huang
CORR
2007
Springer
100views Education» more  CORR 2007»
15 years 6 months ago
Identifying statistical dependence in genomic sequences via mutual information estimates
Questions of understanding and quantifying the representation and amount of information in organisms have become a central part of biological research, as they potentially hold th...
H. M. Aktulga, I. Kontoyiannis, L. A. Lyznik, Luka...