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BIOINFORMATICS
2007
90views more  BIOINFORMATICS 2007»
15 years 6 months ago
HAPLOPOOL: improving haplotype frequency estimation through DNA pools and phylogenetic modeling
In the context of disease association studies, haplotype frequencies are usually estimated from genotype data. In order to reduce genotyping costs, one can estimate the haplotype ...
Bonnie Kirkpatrick, Carlos Santos Armendariz, Rich...
BMCBI
2008
172views more  BMCBI 2008»
15 years 6 months ago
Classification of drug molecules considering their IC50 values using mixed-integer linear programming based hyper-boxes method
Background: A priori analysis of the activity of drugs on the target protein by computational approaches can be useful in narrowing down drug candidates for further experimental t...
Pelin Armutlu, Muhittin Emre Ozdemir, Fadime Ü...
BMCBI
2007
107views more  BMCBI 2007»
15 years 6 months ago
Progressive multiple sequence alignments from triplets
Motivation: The quality of progressive sequence alignments strongly depends on the accuracy of the individual pairwise alignment steps since gaps that are introduced at one step c...
Matthias Kruspe, Peter F. Stadler
BMCBI
2008
146views more  BMCBI 2008»
15 years 6 months ago
ProLoc-GO: Utilizing informative Gene Ontology terms for sequence-based prediction of protein subcellular localization
Background: Gene Ontology (GO) annotation, which describes the function of genes and gene products across species, has recently been used to predict protein subcellular and subnuc...
Wen-Lin Huang, Chun-Wei Tung, Shih-Wen Ho, Shiow-F...
CGF
2010
132views more  CGF 2010»
15 years 6 months ago
Hybrid Booleans
In this paper we present a novel method to compute Boolean operations on polygonal meshes. Given a Boolean expression over an arbitrary number of input meshes we reliably and effi...
Darko Pavic, Marcel Campen, Leif Kobbelt
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