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BMCBI
2011
15 years 1 months ago
Multivariate analysis of microarray data: differential expression and differential connection
Background: Typical analysis of microarray data ignores the correlation between gene expression values. In this paper we present a model for microarray data which specifically all...
Harri T. Kiiveri
BMCBI
2007
173views more  BMCBI 2007»
15 years 6 months ago
Recursive Cluster Elimination (RCE) for classification and feature selection from gene expression data
Background: Classification studies using gene expression datasets are usually based on small numbers of samples and tens of thousands of genes. The selection of those genes that a...
Malik Yousef, Segun Jung, Louise C. Showe, Michael...
BMCBI
2010
97views more  BMCBI 2010»
15 years 6 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg
NIPS
2001
15 years 8 months ago
Global Coordination of Local Linear Models
High dimensional data that lies on or near a low dimensional manifold can be described by a collection of local linear models. Such a description, however, does not provide a glob...
Sam T. Roweis, Lawrence K. Saul, Geoffrey E. Hinto...
BMCBI
2010
118views more  BMCBI 2010»
15 years 6 months ago
Bacillus anthracis genome organization in light of whole transcriptome sequencing
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...