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BCB
2010
126views Bioinformatics» more  BCB 2010»
15 years 1 months ago
Functional similarities of reaction sets in metabolic pathways
Analyzing metabolic pathways by means of their steady states has proven to be accurate and efficient for practical purposes. The models such as elementary flux modes (EFMs) and ex...
Ferhat Ay, Tamer Kahveci
BMCBI
2010
97views more  BMCBI 2010»
15 years 1 months ago
A semi-parametric Bayesian model for unsupervised differential co-expression analysis
Background: Differential co-expression analysis is an emerging strategy for characterizing disease related dysregulation of gene expression regulatory networks. Given pre-defined ...
Johannes M. Freudenberg, Siva Sivaganesan, Michael...
BMCBI
2010
145views more  BMCBI 2010»
15 years 1 months ago
Directionality in protein fold prediction
Background: Ever since the ground-breaking work of Anfinsen et al. in which a denatured protein was found to refold to its native state, it has been frequently stated by the prote...
Jonathan J. Ellis, Fabien P. E. Huard, Charlotte M...
BMCBI
2010
125views more  BMCBI 2010»
15 years 1 months ago
ProbFAST: Probabilistic Functional Analysis System Tool
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...
Israel T. da Silva, Ricardo Z. N. Vêncio, Th...
BMCBI
2010
219views more  BMCBI 2010»
15 years 1 months ago
BiologicalNetworks 2.0 - an integrative view of genome biology data
Background: A significant problem in the study of mechanisms of an organism's development is the elucidation of interrelated factors which are making an impact on the differe...
Sergey Kozhenkov, Yulia Dubinina, Mayya Sedova, Am...
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