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BMCBI
2010
117views more  BMCBI 2010»
15 years 6 months ago
New decoding algorithms for Hidden Markov Models using distance measures on labellings
Background: Existing hidden Markov model decoding algorithms do not focus on approximately identifying the sequence feature boundaries. Results: We give a set of algorithms to com...
Daniel G. Brown 0001, Jakub Truszkowski
BMCBI
2010
205views more  BMCBI 2010»
15 years 6 months ago
A fast indexing approach for protein structure comparison
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
Lei Zhang, James Bailey, Arun Siddharth Konagurthu...
BMCBI
2010
123views more  BMCBI 2010»
15 years 6 months ago
Decoding HMMs using the k best paths: algorithms and applications
Background: Traditional algorithms for hidden Markov model decoding seek to maximize either the probability of a state path or the number of positions of a sequence assigned to th...
Daniel G. Brown 0001, Daniil Golod
BMCBI
2010
149views more  BMCBI 2010»
15 years 6 months ago
S3DB core: a framework for RDF generation and management in bioinformatics infrastructures
Background: Biomedical research is set to greatly benefit from the use of semantic web technologies in the design of computational infrastructure. However, beyond well defined res...
Jonas S. Almeida, Helena F. Deus, Wolfgang Maass
BMCBI
2007
136views more  BMCBI 2007»
15 years 6 months ago
Reduced modeling of signal transduction - a modular approach
Background: Combinatorial complexity is a challenging problem in detailed and mechanistic mathematical modeling of signal transduction. This subject has been discussed intensively...
Markus Koschorreck, Holger Conzelmann, Sybille Ebe...