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BMCBI
2008
175views more  BMCBI 2008»
15 years 6 months ago
Comprehensive inventory of protein complexes in the Protein Data Bank from consistent classification of interfaces
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...
Andrew J. Bordner, Andrey A. Gorin
BMCBI
2008
145views more  BMCBI 2008»
15 years 6 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
VR
2008
IEEE
120views Virtual Reality» more  VR 2008»
15 years 6 months ago
Force modeling for tooth preparation in a dental training system
Feedback force is very important for novices to simulate tooth preparation by using the haptic interaction system (dental training system) in a virtual environment. In the process ...
Guanyang Liu, Yuru Zhang, William T. Townsend
NAR
2007
91views more  NAR 2007»
15 years 6 months ago
SuperHapten: a comprehensive database for small immunogenic compounds
The immune system protects organisms from foreign proteins, peptide epitopes and a multitude of chemical compounds. Among these, haptens are small molecules, eliciting an immune r...
Stefan Günther, Dorothea Hempel, Mathias Dunk...