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BMCBI
2007
102views more  BMCBI 2007»
15 years 7 months ago
Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
Mark C. Emerick, Giovanni Parmigiani, William S. A...
BMCBI
2007
181views more  BMCBI 2007»
15 years 7 months ago
Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D
Background: Macromolecular visualization as well as automated structural and functional annotation tools play an increasingly important role in the post-genomic era, contributing ...
Aleksey A. Porollo, Jaroslaw Meller
BMCBI
2008
160views more  BMCBI 2008»
15 years 7 months ago
Cross-species and cross-platform gene expression studies with the Bioconductor-compliant R package 'annotationTools'
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
Alexandre Kuhn, Ruth Luthi-Carter, Mauro Delorenzi
BMCBI
2008
116views more  BMCBI 2008»
15 years 7 months ago
Structuring an event ontology for disease outbreak detection
Background: This paper describes the design of an event ontology being developed for application in the machine understanding of infectious disease-related events reported in natu...
Ai Kawazoe, Hutchatai Chanlekha, Mika Shigematsu, ...
COMPUTER
2008
84views more  COMPUTER 2008»
15 years 7 months ago
e-Science, caGrid, and Translational Biomedical Research
We describe the informatics requirements of translational biomedical research projects and how e-Science tools can be used to address them. We use pattern templates to describe the...
Joel H. Saltz, Tahsin M. Kurç, Shannon Hast...
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