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BMCBI
2010
146views more  BMCBI 2010»
15 years 6 months ago
On the Choice and Number of Microarrays for Transcriptional Regulatory Network Inference
Background: Transcriptional regulatory network inference (TRNI) from large compendia of DNA microarrays has become a fundamental approach for discovering transcription factor (TF)...
Elissa J. Cosgrove, Timothy S. Gardner, Eric D. Ko...
BMCBI
2008
202views more  BMCBI 2008»
15 years 6 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2007
119views more  BMCBI 2007»
15 years 6 months ago
A dynamic programming approach for the alignment of signal peaks in multiple gas chromatography-mass spectrometry experiments
Background: Gas chromatography-mass spectrometry (GC-MS) is a robust platform for the profiling of certain classes of small molecules in biological samples. When multiple samples ...
Mark D. Robinson, David P. De Souza, Woon Wai Keen...
BMCBI
2008
179views more  BMCBI 2008»
15 years 6 months ago
Building pathway clusters from Random Forests classification using class votes
Background: Recent years have seen the development of various pathway-based methods for the analysis of microarray gene expression data. These approaches have the potential to bri...
Herbert Pang, Hongyu Zhao
BMCBI
2010
132views more  BMCBI 2010»
15 years 6 months ago
Data structures and compression algorithms for high-throughput sequencing technologies
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
Kenny Daily, Paul Rigor, Scott Christley, Xiaohui ...