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BMCBI
2010
110views more  BMCBI 2010»
15 years 7 months ago
Towards the systematic discovery of signal transduction networks using phosphorylation dynamics data
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...
Haruna Imamura, Nozomu Yachie, Rintaro Saito, Yasu...
BMCBI
2010
110views more  BMCBI 2010»
15 years 7 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...
BMCBI
2007
80views more  BMCBI 2007»
15 years 7 months ago
A network perspective on the topological importance of enzymes and their phylogenetic conservation
Background: A metabolic network is the sum of all chemical transformations or reactions in the cell, with the metabolites being interconnected by enzyme-catalyzed reactions. Many ...
Wei-chung Liu, Wen-hsien Lin, Andrew J. Davis, Fer...
BMCBI
2008
154views more  BMCBI 2008»
15 years 7 months ago
GeNESiS: gene network evolution simulation software
Background: There has been a lot of interest in recent years focusing on the modeling and simulation of Gene Regulatory Networks (GRNs). However, the evolutionary mechanisms that ...
Anton Kratz, Masaru Tomita, Arun Krishnan
180
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CORR
2006
Springer
119views Education» more  CORR 2006»
15 years 6 months ago
Network Inference from Co-Occurrences
The study of networked systems is an emerging field, impacting almost every area of engineering and science, including the important domains of communication systems, biology, soc...
Michael Rabbat, Mário A. T. Figueiredo, Rob...