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BMCBI
2010
150views more  BMCBI 2010»
15 years 6 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
NECO
2008
108views more  NECO 2008»
15 years 6 months ago
Optimization of Decision Making in Multilayer Networks: The Role of Locus Coeruleus
Previous theoretical work has shown that a single layer neural network can implement the optimal decision process for simple, two alternative forced choice (2AFC) tasks. However, ...
Eric Shea-Brown, Mark S. Gilzenrat, Jonathan D. Co...
BMCBI
2005
98views more  BMCBI 2005»
15 years 6 months ago
Iterative approach to model identification of biological networks
Background: Recent advances in molecular biology techniques provide an opportunity for developing detailed mathematical models of biological processes. An iterative scheme is intr...
Kapil G. Gadkar, Rudiyanto Gunawan, Francis J. Doy...
TSC
2008
209views more  TSC 2008»
15 years 6 months ago
Effective Web Service Composition in Diverse and Large-Scale Service Networks
Web services are considered to be a potential silver bullet for the envisioned Service Oriented Architecture, in which loosely coupled software components are published, located, a...
Seog-Chan Oh, Dongwon Lee, Soundar R. T. Kumara
JCNS
2002
99views more  JCNS 2002»
15 years 6 months ago
Coarse-Grained Reduction and Analysis of a Network Model of Cortical Response: I. Drifting Grating Stimuli
We present a reduction of a large-scale network model of visual cortex developed by McLaughlin, Shapley, Shelley, and Wielaard. The reduction is from many integrate-and-fire neuron...
Michael Shelley, David McLaughlin