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BIOINFORMATICS
2011
14 years 10 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
JAMIA
2011
94views more  JAMIA 2011»
14 years 9 months ago
Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence
Objective Uncovering the dominant molecular deregulation among the multitude of pathways implicated in aggressive prostate cancer is essential to intelligently developing targeted...
James L. Chen, Jianrong Li, Walter M. Stadler, Yve...
NAR
2011
195views Computer Vision» more  NAR 2011»
14 years 9 months ago
MitoGenesisDB: an expression data mining tool to explore spatio-temporal dynamics of mitochondrial biogenesis
Mitochondria constitute complex and flexible cellular entities, which play crucial roles in normal and pathological cell conditions. The database MitoGenesisDB focuses on the dyna...
Jean-Christophe Gelly, Mickael Orgeur, Claude Jacq...
NAR
2011
214views Computer Vision» more  NAR 2011»
14 years 9 months ago
IEDB-3D: structural data within the immune epitope database
IEDB-3D is the 3D structural component of the Immune Epitope Database (IEDB) available via the ‘Browse by 3D Structure’ page at http://www.iedb .org. IEDB-3D catalogs B- and T...
Julia V. Ponomarenko, Nikitas Papangelopoulos, Dir...
NAR
2011
159views Computer Vision» more  NAR 2011»
14 years 9 months ago
SuperSweet - a resource on natural and artificial sweetening agents
A vast number of sweet tasting molecules are known, encompassing small compounds, carbohydrates, D-amino acids and large proteins. Carbohydrates play a particularly big role in hu...
Jessica Ahmed, Saskia Preissner, Mathias Dunkel, C...