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BMCBI
2007
158views more  BMCBI 2007»
15 years 7 months ago
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
Corinne Dahinden, Giovanni Parmigiani, Mark C. Eme...
BMCBI
2006
99views more  BMCBI 2006»
15 years 7 months ago
Genetic algorithm learning as a robust approach to RNA editing site prediction
Background: RNA editing is one of several post-transcriptional modifications that may contribute to organismal complexity in the face of limited gene complement in a genome. One f...
James Thompson, Shuba Gopal
BMCBI
2006
113views more  BMCBI 2006»
15 years 7 months ago
QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...
CSDA
2006
84views more  CSDA 2006»
15 years 7 months ago
Performing hypothesis tests on the shape of functional data
We explore different approaches for performing hypothesis tests on the shape of a mean function by developing general methodologies both, for the often assumed, i.i.d. error struc...
Gareth M. James, Ashish Sood
BMCBI
2007
147views more  BMCBI 2007»
15 years 7 months ago
Bias in random forest variable importance measures: Illustrations, sources and a solution
Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in bioinformatics and relate...
Carolin Strobl, Anne-Laure Boulesteix, Achim Zeile...