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BMCBI
2006
102views more  BMCBI 2006»
15 years 6 months ago
MycoperonDB: a database of computationally identified operons and transcriptional units in Mycobacteria
Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
Sarita Ranjan, Ranjit Kumar Gundu, Akash Ranjan
BMCBI
2007
107views more  BMCBI 2007»
15 years 6 months ago
A computational approach for detecting peptidases and their specific inhibitors at the genome level
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...
Lisa Bartoli, Remo Calabrese, Piero Fariselli, Dam...
BMCBI
2004
207views more  BMCBI 2004»
15 years 6 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...
BMCBI
2004
151views more  BMCBI 2004»
15 years 6 months ago
A computational approach for ordering signal transduction pathway components from genomics and proteomics Data
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
Yin Liu, Hongyu Zhao
BMCBI
2011
15 years 1 months ago
A Computational Framework for Proteome-Wide Pursuit and Prediction of Metalloproteins using ICP-MS and MS/MS Data
Background: Metal-containing proteins comprise a diverse and sizable category within the proteomes of organisms, ranging from proteins that use metals to catalyze reactions to pro...
W. Andrew Lancaster, Jeremy L. Praissman, Farris L...