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ALMOB
2008
95views more  ALMOB 2008»
15 years 6 months ago
A stitch in time: Efficient computation of genomic DNA melting bubbles
Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
Eivind Tøstesen
BMCBI
2010
141views more  BMCBI 2010»
15 years 6 months ago
Computing and visually analyzing mutual information in molecular co-evolution
Background: Selective pressure in molecular evolution leads to uneven distributions of amino acids and nucleotides. In fact one observes correlations among such constituents due t...
Sebastian Bremm, Tobias Schreck, Patrick Boba, Ste...
BMCBI
2010
121views more  BMCBI 2010»
15 years 4 months ago
Computing DNA duplex instability profiles efficiently with a two-state model: trends of promoters and binding sites
Background: DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter ac...
Miriam R. Kantorovitz, Zoi Rapti, Vladimir Gelev, ...
KDD
2004
ACM
124views Data Mining» more  KDD 2004»
16 years 7 months ago
Eigenspace-based anomaly detection in computer systems
We report on an automated runtime anomaly detection method at the application layer of multi-node computer systems. Although several network management systems are available in th...
Hisashi Kashima, Tsuyoshi Idé
BIBE
2003
IEEE
133views Bioinformatics» more  BIBE 2003»
15 years 12 months ago
A Computational Pipeline for Protein Structure Prediction and Analysis at Genome Scale
The tertiary (3D) structure of a protein contains the essential information for understanding the biological function of the protein at the molecular and cellular levels. Traditio...
Manesh J. Shah, Sergei Passovets, Dongsup Kim, Kyl...