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GCB
1997
Springer
77views Biometrics» more  GCB 1997»
15 years 10 months ago
Statistics of large scale sequence searching
Motivation: Database search programs such as FASTA, BLAST or a rigorous Smith–Waterman algorithm produce lists of database entries, which are assumed to be related to the query....
Rainer Spang, Martin Vingron
BIOCOMP
2006
15 years 8 months ago
Performance of Sequence Alignment Bioinformatics Applications on General Purpose Processors: A Case Study
- Aligning specific sequences against other known sequences in a database is a central aspect of bioinformatics. New experimental data being added continuously to these databases n...
Pradeep Nair, Eugene John
ISMB
1994
15 years 7 months ago
Optimally Parsing a Sequence into Different Classes Based on Multiple Types of Evidence
Weconsider the problem of parsing a sequence into different classes of subsequences.Twocommonexamplesare finding the exons and introns in genomicsequences and identifying the seco...
Gary D. Stormo, David Haussler
BIB
2010
68views more  BIB 2010»
15 years 6 months ago
Genome variation discovery with high-throughput sequencing data
The advent of high-throughput sequencing (HTS) technologies is enabling sequencing of human genomes at a significantly lower cost. The availability of these genomes is hoped to en...
Adrian V. Dalca, Michael Brudno
JPDC
2006
112views more  JPDC 2006»
15 years 6 months ago
Large scale multiple sequence alignment with simultaneous phylogeny inference
Multiple sequence alignment (MSA) and phylogenetic tree reconstruction are one of the most important problems in the computational biology. While both these problems are of great ...
Gilles Parmentier, Denis Trystram, Jaroslaw Zola