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ALMOB
2006
138views more  ALMOB 2006»
15 years 6 months ago
A combinatorial optimization approach for diverse motif finding applications
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
Elena Zaslavsky, Mona Singh
BMCBI
2006
145views more  BMCBI 2006»
15 years 6 months ago
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
BMCBI
2006
102views more  BMCBI 2006»
15 years 6 months ago
UVPAR: fast detection of functional shifts in duplicate genes
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
Vicente Arnau, Miguel Gallach, J. Ignasi Lucas, Ig...
GC
2008
Springer
15 years 6 months ago
Laplacian Spectrum of Weakly Quasi-threshold Graphs
In this paper we study the class of weakly quasi-threshold graphs that are obtained from a vertex by recursively applying the operations (i) adding a new isolated vertex, (ii) addi...
R. B. Bapat, A. K. Lal, Sukanta Pati
BMCBI
2006
95views more  BMCBI 2006»
15 years 6 months ago
XcisClique: analysis of regulatory bicliques
Background: Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs si...
Amrita Pati, Cecilia Vasquez-Robinet, Lenwood S. H...
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