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BMCBI
2008
142views more  BMCBI 2008»
15 years 6 months ago
Optimal neighborhood indexing for protein similarity search
Background: Similarity inference, one of the main bioinformatics tasks, has to face an exponential growth of the biological data. A classical approach used to cope with this data ...
Pierre Peterlongo, Laurent Noé, Dominique L...
BMCBI
2007
147views more  BMCBI 2007»
15 years 6 months ago
Bias in random forest variable importance measures: Illustrations, sources and a solution
Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in bioinformatics and relate...
Carolin Strobl, Anne-Laure Boulesteix, Achim Zeile...
JCB
2008
90views more  JCB 2008»
15 years 6 months ago
A Simple Model of the Modular Structure of Transcriptional Regulation in Yeast
Resolving the general organizational principles that govern the interactions during transcriptional gene regulation has great relevance for understanding disease progression, biof...
Vladimir Filkov, Nameeta Shah
CORR
2007
Springer
105views Education» more  CORR 2007»
15 years 6 months ago
Relative-Error CUR Matrix Decompositions
Many data analysis applications deal with large matrices and involve approximating the matrix using a small number of “components.” Typically, these components are linear combi...
Petros Drineas, Michael W. Mahoney, S. Muthukrishn...
EOR
2007
101views more  EOR 2007»
15 years 6 months ago
Optimizing an objective function under a bivariate probability model
The motivation of this paper is to obtain an analytical closed form of a quadratic objective function arising from a stochastic decision process with bivariate exponential probabi...
Xavier Brusset, Nico M. Temme