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» Computational methods for case-cohort studies
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HUC
2010
Springer
15 years 7 months ago
Modeling people's place naming preferences in location sharing
Most location sharing applications display people's locations on a map. However, people use a rich variety of terms to refer to their locations, such as "home," &qu...
Jialiu Lin, Guang Xiang, Jason I. Hong, Norman M. ...
BMCBI
2008
155views more  BMCBI 2008»
15 years 6 months ago
AMMOS: Automated Molecular Mechanics Optimization tool for in silico Screening
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...
Tania Pencheva, David Lagorce, Ilza Pajeva, Bruno ...
BMCBI
2010
119views more  BMCBI 2010»
15 years 6 months ago
A comparison of internal validation techniques for multifactor dimensionality reduction
Background: It is hypothesized that common, complex diseases may be due to complex interactions between genetic and environmental factors, which are difficult to detect in high-di...
Stacey J. Winham, Andrew J. Slater, Alison A. Mots...
ALMOB
2006
155views more  ALMOB 2006»
15 years 6 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
BMCBI
2006
108views more  BMCBI 2006»
15 years 6 months ago
Probe set algorithms: is there a rational best bet?
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Jinwook Seo, Eric P. Hoffman