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BMCBI
2007
144views more  BMCBI 2007»
15 years 6 months ago
Robust regression for periodicity detection in non-uniformly sampled time-course gene expression data
Background: In practice many biological time series measurements, including gene microarrays, are conducted at time points that seem to be interesting in the biologist's opin...
Miika Ahdesmäki, Harri Lähdesmäki, ...
BMCBI
2008
96views more  BMCBI 2008»
15 years 6 months ago
The value of position-specific scoring matrices for assessment of protein allegenicity
Background: Bioinformatics tools are commonly used for assessing potential protein allergenicity. While these methods have achieved good accuracies for highly conserved sequences,...
Shen Jean Lim, Joo Chuan Tong, Fook Tim Chew, Mart...
BMCBI
2006
160views more  BMCBI 2006»
15 years 6 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
BMCBI
2007
163views more  BMCBI 2007»
15 years 6 months ago
Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approac
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Carmen Pin, Mark Reuter
BMCBI
2005
98views more  BMCBI 2005»
15 years 6 months ago
The effects of normalization on the correlation structure of microarray data
Background: Stochastic dependence between gene expression levels in microarray data is of critical importance for the methods of statistical inference that resort to pooling test-...
Xing Qiu, Andrew I. Brooks, Lev Klebanov, Andrei Y...