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ICCS
2009
Springer
16 years 1 months ago
Experience with Approximations in the Trust-Region Parallel Direct Search Algorithm
Recent years have seen growth in the number of algorithms designed to solve challenging simulation-based nonlinear optimization problems. One such algorithm is the Trust-Region Par...
S. M. Shontz, V. E. Howle, P. D. Hough
IPPS
2006
IEEE
16 years 17 days ago
Parallel implementation of the replica exchange molecular dynamics algorithm on Blue Gene/L
The Replica Exchange method is a popular approach for studying the folding thermodynamics of small to modest size proteins in explicit solvent, since it is easily parallelized. Ho...
Maria Eleftheriou, Aleksandr Rayshubskiy, Jed W. P...
ICPPW
2009
IEEE
15 years 4 months ago
Analyzing Checkpointing Trends for Applications on the IBM Blue Gene/P System
Current petascale systems have tens of thousands of hardware components and complex system software stacks, which increase the probability of faults occurring during the lifetime ...
Harish Gapanati Naik, Rinku Gupta, Pete Beckman
BMCBI
2008
87views more  BMCBI 2008»
15 years 6 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
RECOMB
2002
Springer
16 years 6 months ago
Simulating a Coalescent Process with Recombination and Ascertainment
A new method is presented for use in simulating samples of disease and normal chromosomes bearing multiple linked genetic markers under a neutral model of mutation, genetic drift, ...
Ying Wang, Bruce Rannala