17185 search results - page 3351 / 3437 » Computational and Quantitative Studies |
156
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BMCBI
2010
15 years 6 months ago
2010
Background: DNA sequence comparison is a well-studied problem, in which two DNA sequences are compared using a weighted edit distance. Recent DNA sequencing technologies however o...
169
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BMCBI
2010
15 years 6 months ago
2010
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
179
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BMCBI
2010
15 years 6 months ago
2010
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
146
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BMCBI
2010
15 years 6 months ago
2010
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
183
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BMCBI
2010
15 years 6 months ago
2010
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...