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BMCBI
2007
124views more  BMCBI 2007»
15 years 6 months ago
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
G. Traver Hart, Insuk Lee, Edward M. Marcotte
IEEEPACT
2003
IEEE
15 years 12 months ago
Biomedical Computing and Visualization
Computers have changed the way we live, work, and even recreate. Now, they are transforming how we think about and treat human disease. In particular, advanced techniques in biome...
Chris Johnson
RECOMB
2003
Springer
16 years 7 months ago
Optimizing exact genetic linkage computations
Genetic linkage analysis is a challenging application which requires Bayesian networks consisting of thousands of vertices. Consequently, computing the likelihood of data, which i...
Dan Geiger, Maáyan Fishelson
COMPGEOM
2004
ACM
16 years 4 days ago
A computational framework for incremental motion
We propose a generic computational framework for maintaining a discrete geometric structure defined by a collection of static and mobile objects. We assume that the mobile object...
David M. Mount, Nathan S. Netanyahu, Christine D. ...
ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
15 years 6 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki