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» Computational Challenges of Systems Biology
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BMCBI
2006
118views more  BMCBI 2006»
15 years 6 months ago
Low degree metabolites explain essential reactions and enhance modularity in biological networks
Background: Recently there has been a lot of interest in identifying modules at the level of genetic and metabolic networks of organisms, as well as in identifying single genes an...
Areejit Samal, Shalini Singh, Varun Giri, Sandeep ...
BMCBI
2010
125views more  BMCBI 2010»
15 years 1 months ago
ProbFAST: Probabilistic Functional Analysis System Tool
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...
Israel T. da Silva, Ricardo Z. N. Vêncio, Th...
BIOINFORMATICS
2011
15 years 1 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj
BICOB
2011
Springer
14 years 6 months ago
A Systematic Approach to Evaluate Sustained Stochastic Oscillations
Although the populations of biological systems are inherently discrete and their dynamics are strongly stochastic, it is usual to consider their limiting behaviour for large envir...
Jorge Júlvez, Marta Z. Kwiatkowska, Gethin ...
ASM
2008
ASM
15 years 8 months ago
Model Based Refinement and the Tools of Tomorrow
The ingredients of typical model based development via refinement are re-examined, and some well known frameworks are reviewed in that light, drawing out commonalities and differen...
Richard Banach