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» Computational Challenges of Systems Biology
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BMCBI
2007
131views more  BMCBI 2007»
15 years 6 months ago
Prediction of peptides observable by mass spectrometry applied at the experimental set level
Background: When proteins are subjected to proteolytic digestion and analyzed by mass spectrometry using a method such as 2D LC MS/MS, only a portion of the proteotypic peptides a...
William S. Sanders, Susan M. Bridges, Fiona M. McC...
JCC
2006
110views more  JCC 2006»
15 years 6 months ago
Using internal and collective variables in Monte Carlo simulations of nucleic acid structures: Chain breakage/closure algorithm
: This article describes a method for solving the geometric closure problem for simplified models of nucleic acid structures by using the constant bond lengths approximation. The r...
Heinz Sklenar, Daniel Wüstner, Remo Rohs
181
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BMCBI
2011
14 years 10 months ago
FFCA: a feasibility-based method for flux coupling analysis of metabolic networks
Background: Flux coupling analysis (FCA) is a useful method for finding dependencies between fluxes of a metabolic network at steady-state. FCA classifies reactions into subsets (...
László Dávid, Sayed-Amir Mara...
SIGMOD
2010
ACM
324views Database» more  SIGMOD 2010»
15 years 11 months ago
Similarity search and locality sensitive hashing using ternary content addressable memories
Similarity search methods are widely used as kernels in various data mining and machine learning applications including those in computational biology, web search/clustering. Near...
Rajendra Shinde, Ashish Goel, Pankaj Gupta, Debojy...
BMCBI
2006
146views more  BMCBI 2006»
15 years 6 months ago
Optimized Particle Swarm Optimization (OPSO) and its application to artificial neural network training
Background: Particle Swarm Optimization (PSO) is an established method for parameter optimization. It represents a population-based adaptive optimization technique that is influen...
Michael Meissner, Michael Schmuker, Gisbert Schnei...