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» Computational Challenges of Systems Biology
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RECOMB
2007
Springer
16 years 6 months ago
Learning Gene Regulatory Networks via Globally Regularized Risk Minimization
Learning the structure of a gene regulatory network from time-series gene expression data is a significant challenge. Most approaches proposed in the literature to date attempt to ...
Yuhong Guo, Dale Schuurmans
RECOMB
2006
Springer
16 years 6 months ago
A Patient-Gene Model for Temporal Expression Profiles in Clinical Studies
Abstract. Pharmacogenomics and clinical studies that measure the temporal expression levels of patients can identify important pathways and biomarkers that are activated during dis...
Naftali Kaminski, Ziv Bar-Joseph
ISMB
1994
15 years 8 months ago
Representations of Metabolic Knowledge: Pathways
The automatic generation of drawings of metabolic pathways is a challenging problem that depends intimately on exactly what information has been recorded for each pathway, and on ...
Peter D. Karp, Suzanne M. Paley
JOBIM
2000
15 years 10 months ago
InterDB, a Prediction-Oriented Protein Interaction Database for C. elegans
Protein-protein interactions are critical to many biological processes, extending from the formation of cellular macromolecular structures and enzymatic complexes to the regulation...
Nicolas Thierry-Mieg, Laurent Trilling
IAT
2003
IEEE
15 years 12 months ago
Assistive Ecologies - Bio-mimetic Design Of Ambient Intelligence
Facing great challenges in designing better assistive technology with ever more complex and pervasive IT systems we need a general change in our understanding of designing IT. Way...
Mikkel Holm Sørensen