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» Computational Challenges of Systems Biology
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RECOMB
2006
Springer
16 years 6 months ago
Probabilistic Paths for Protein Complex Inference
Understanding how individual proteins are organized into complexes and pathways is a significant current challenge. We introduce new algorithms to infer protein complexes by combin...
Hailiang Huang, Lan V. Zhang, Frederick P. Roth, J...
ICAC
2009
IEEE
16 years 1 months ago
Ranking the importance of alerts for problem determination in large computer systems
The complexity of large computer systems has raised unprecedented challenges for system management. In practice, operators often collect large volume of monitoring data from system...
Guofei Jiang, Haifeng Chen, Kenji Yoshihira, Akhil...
ISVC
2009
Springer
15 years 11 months ago
A 3D Active Surface Model for the Accurate Segmentation of Drosophila Schneider Cell Nuclei and Nucleoli
Abstract. We present an active surface model designed for the segmentation of Drosophila Schneider cell nuclei and nucleoli from wide-field microscopic data. The imaging technique...
Margret Keuper, Jan Padeken, Patrick Heun, Hans Bu...
AB
2007
Springer
16 years 21 days ago
A Stochastic Pi Calculus for Concurrent Objects
We present SpiCO, a new modeling and simulation language for systems biology. SpiCO is based on the stochastic π-calculus. It supports higher level modeling via multi-profile con...
Céline Kuttler, Cédric Lhoussaine, J...
ISMB
1997
15 years 7 months ago
SEALS: A System for Easy Analysis of Lots of Sequences
We present a system of programs designed to facilitate sequence analysis projects involving large amounts of data. SEALS (System for Easy Analysis of Lots of Sequences) is a logic...
D. Roland Walker, Eugene V. Koonin