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» Computational Challenges of Systems Biology
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ISMB
1998
15 years 7 months ago
Identification of Divergent Functions in Homologous Proteins by Induction over Conserved Modules
Homologousproteins do not necessarily exhibit identical biochemicalfunction. Despitethis fact, local or global sequence similarity is widely used as an indication of functional id...
Imran Shah, Lawrence Hunter
ISMB
2000
15 years 7 months ago
A Statistical Method for Finding Transcription Factor Binding Sites
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
Saurabh Sinha, Martin Tompa
ISSADS
2005
Springer
15 years 12 months ago
Database System Architecture - A Walk Through Time: From Centralized Platform to Mobile Computing - Keynote Address
Classical distributed database systems monolithically offer distribution transparency and higher performance. This is made possible by making data available and closer to the appl...
Ali R. Hurson, Yu Jiao
ICS
2007
Tsinghua U.
16 years 18 days ago
Scheduling FFT computation on SMP and multicore systems
Increased complexity of memory systems to ameliorate the gap between the speed of processors and memory has made it increasingly harder for compilers to optimize an arbitrary code...
Ayaz Ali, S. Lennart Johnsson, Jaspal Subhlok
PDP
2008
IEEE
16 years 25 days ago
System-Level Virtualization for High Performance Computing
System-level virtualization has been a research topic since the 70’s but regained popularity during the past few years because of the availability of efficient solution such as...
Geoffroy Vallée, Thomas Naughton, Christian...