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» Computational Challenges of Systems Biology
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BMCBI
2007
114views more  BMCBI 2007»
15 years 6 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
RECOMB
2000
Springer
15 years 10 months ago
Universal DNA tag systems: a combinatorial design scheme
Custom-designed DNA arrays offer the possibility of simultaneously monitoring thousands of hybridization reactions. These arrays show great potential for many medical and scientif...
Amir Ben-Dor, Richard M. Karp, Benno Schwikowski, ...
ICCS
2003
Springer
15 years 11 months ago
Towards Biomedical Problem Solving in a Game Environment
Biomedical systems involve complex interactions between diverse components. Problem solving in such systems requires insight, i.e. the capability to make non-obvious connections. I...
Yang Cai 0002, Ingo Snel, B. Suman Bharathi, Cleme...
CIBCB
2009
IEEE
15 years 7 months ago
Application of machine learning approaches on quantitative structure activity relationships
Machine Learning techniques are successfully applied to establish quantitative relations between chemical structure and biological activity (QSAR), i.e. classify compounds as activ...
Mariusz Butkiewicz, Ralf Mueller, Danilo Selic, Er...
COMPSAC
2004
IEEE
15 years 10 months ago
Materializing Ubiquitous Computing Environments
A key challenge in ubiquitous computing is how to manage ambient information about the environment where a variety of devices appear. Traditional capability descriptions are inadeq...
Kimio Kuramitsu, Hideyuki Tokuda