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BMCBI
2007
146views more  BMCBI 2007»
15 years 6 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2007
144views more  BMCBI 2007»
15 years 6 months ago
Gene analogue finder: a GRID solution for finding functionally analogous gene products
Background: To date more than 2,1 million gene products from more than 100000 different species have been described specifying their function, the processes they are involved in a...
Angelica Tulipano, Giacinto Donvito, Flavio Licciu...
BMCBI
2007
142views more  BMCBI 2007»
15 years 6 months ago
SABERTOOTH: protein structural alignment based on a vectorial structure representation
Background: The task of computing highly accurate structural alignments of proteins in very short computation time is still challenging. This is partly due to the complexity of pr...
Florian Teichert, Ugo Bastolla, Markus Porto
BMCBI
2007
164views more  BMCBI 2007»
15 years 6 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
ICPPW
2009
IEEE
15 years 3 months ago
A Scalable Parallel Approach for Peptide Identification from Large-Scale Mass Spectrometry Data
Identifying peptides, which are short polymeric chains of amino acid residues in a protein sequence, is of fundamental importance in systems biology research. The most popular appr...
Gaurav Ramesh Kulkarni, Ananth Kalyanaraman, Willi...