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ISMB
2000
15 years 8 months ago
An Evaluation of Ontology Exchange Languages for Bioinformatics
Ontologies are specifications of the concepts in a given field, and of the relationships among those concepts. The development of ontologies for molecular-biology information and ...
Robin McEntire, Peter D. Karp, Neil F. Abernethy, ...
ISMB
2000
15 years 8 months ago
Pattern Recognition of Genomic Features with Microarrays: Site Typing of Mycobacterium Tuberculosis Strains
Mycobacterium tuberculosis (M. tb.) strains differ in the number and locations of a transposon-like insertion sequence known as IS6110. Accurate detection of this sequence can be ...
Soumya Raychaudhuri, Joshua M. Stuart, Xuemin Liu,...
ISMB
1996
15 years 7 months ago
A Knowledge-Based Method for Protein Structure Refinement and Prediction
The native conformation of a protein, in a given environment, is determined entirely by the various interatomic interactions dictated by the amino acid sequence (1-3). We describe...
Shankar Subramaniam, David K. Tcheng, James M. Fen...
ISMB
1996
15 years 7 months ago
Gene Recognition in Cyanobacterium Genomic Sequence Data Using the Hidden Markov Model
We have developed a hidden Markov model (HMM)to detect the protein coding regions within one megabase contiguous sequence data, registered in a database called GenBankin eight ent...
Tetsushi Yada, Makoto Hirosawa
ISMB
1994
15 years 7 months ago
Stochastic Motif Extraction Using Hidden Markov Model
In this paper, westudy the application of an ttMM(hidden Markov model) to the problem of representing protein sequencesby a stochastic motif. Astochastic protein motif represents ...
Yukiko Fujiwara, Minoru Asogawa, Akihiko Konagaya