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BIOSYSTEMS
2007
104views more  BIOSYSTEMS 2007»
15 years 6 months ago
New structural variation in evolutionary searches of RNA neutral networks
RNA secondary structure is an important computational model to understand how genetic variation maps into phenotypic (structural) variation. Evolutionary innovation in RNA structu...
Sumedha, Olivier C. Martin, Andreas Wagner
BMCBI
2010
97views more  BMCBI 2010»
15 years 6 months ago
Incorporating significant amino acid pairs to identify O-linked glycosylation sites on transmembrane proteins and non-transmembr
Background: While occurring enzymatically in biological systems, O-linked glycosylation affects protein folding, localization and trafficking, protein solubility, antigenicity, bi...
Shu-An Chen, Tzong-Yi Lee, Yu-Yen Ou
CORR
2008
Springer
90views Education» more  CORR 2008»
15 years 6 months ago
A Pseudo-Boolean Solution to the Maximum Quartet Consistency Problem
Determining the evolutionary history of a given biological data is an important task in biological sciences. Given a set of quartet topologies over a set of taxa, the Maximum Quart...
António Morgado, João P. Marques Sil...
ENTCS
2010
127views more  ENTCS 2010»
15 years 6 months ago
Combining Model Reductions
Molecular biological models usually suffer from a large combinatorial explosion. Indeed, proteins form complexes and modify each others, which leads to the formation of a huge num...
Ferdinanda Camporesi, Jérôme Feret, H...
DAM
2007
91views more  DAM 2007»
15 years 6 months ago
Integer linear programming approaches for non-unique probe selection
In addition to their prevalent use for analyzing gene expression, DNA microarrays are an efficient tool for biological, medical, and industrial applications because of their abil...
Gunnar W. Klau, Sven Rahmann, Alexander Schliep, M...