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EBERNBURG
1990
15 years 10 months ago
Problems of Autonomy and Discontexturality in the Theory of Living Systems
In the theory of living systems any description of self-organizing processes is confronted by a very central problem concerning the role of the system's boundary, i.e., there...
Rudolf Kaehr, E. von Goldammer
243
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ISMB
2008
15 years 9 months ago
Classification of arrayCGH data using fused SVM
Motivation: Array-based comparative genomic hybridization (arrayCGH) has recently become a popular tool to identify DNA copy number variations along the genome. These profiles are...
Franck Rapaport, Emmanuel Barillot, Jean-Philippe ...
ISMB
2004
15 years 8 months ago
Exploiting conserved structure for faster annotation of non-coding RNAs without loss of accuracy
Motivation: Non-coding RNAs (ncRNAs)--functional RNA molecules not coding for proteins--are grouped into hundreds of families of homologs. To find new members of an ncRNA gene fam...
Zasha Weinberg, Walter L. Ruzzo
ISMB
1996
15 years 8 months ago
Refining Neural Network Predictions for Helical Transmembrane Proteins by Dynamic Programming
For transmembrane proteins experimental determina-tion of three-dimensional structure is problematic. However, membrane proteins have important impact for molecular biology in gen...
Burkhard Rost, Rita Casadio, Piero Fariselli
ISMB
1993
15 years 8 months ago
Detection of Correlations in tRNA Sequences with Structural Implications
Using a flexible representation of biological sequences, we have performed a comparative analysis of 1208 known tRNA sequences. We believe we our technique is a more sensitive met...
Tod M. Klingler, Douglas L. Brutlag