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RECOMB
2006
Springer
16 years 7 months ago
Leveraging Information Across HLA Alleles/Supertypes Improves Epitope Prediction
We present a model for predicting HLA class I restricted CTL epitopes. In contrast to almost all other work in this area, we train a single model on epitopes from all HLA alleles a...
David Heckerman, Carl Myers Kadie, Jennifer Listga...
RECOMB
2006
Springer
16 years 7 months ago
A Patient-Gene Model for Temporal Expression Profiles in Clinical Studies
Abstract. Pharmacogenomics and clinical studies that measure the temporal expression levels of patients can identify important pathways and biomarkers that are activated during dis...
Naftali Kaminski, Ziv Bar-Joseph
RECOMB
2006
Springer
16 years 7 months ago
Identification and Evaluation of Functional Modules in Gene Co-expression Networks
Abstract. Identifying gene functional modules is an important step towards elucidating gene functions at a global scale. In this paper, we introduce a simple method to construct ge...
Jianhua Ruan, Weixiong Zhang
RECOMB
2006
Springer
16 years 7 months ago
Probabilistic Paths for Protein Complex Inference
Understanding how individual proteins are organized into complexes and pathways is a significant current challenge. We introduce new algorithms to infer protein complexes by combin...
Hailiang Huang, Lan V. Zhang, Frederick P. Roth, J...
RECOMB
2005
Springer
16 years 7 months ago
Likely Scenarios of Intron Evolution
Whether common ancestors of eukaryotes and prokaryotes had introns is one of the oldest unanswered questions in molecular evolution. Recently completed genome sequences have been u...
Miklós Csürös