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RECOMB
2008
Springer
16 years 7 months ago
Limitations of Pseudogenes in Identifying Gene Losses
The loss of previously established genes has been proposed as a major force in evolutionary change. While the sequencing of many new species offers the opportunity to identify case...
James C. Costello, Mira V. Han, Matthew W. Hahn
RECOMB
2008
Springer
16 years 7 months ago
Estimating the Relative Contributions of New Genes from Retrotransposition and Segmental Duplication Events during Mammalian Evo
Gene duplication has long been recognized as a major force in genome evolution and has recently been recognized as an important source of individual variation. For many years the o...
Jin Jun, Paul Ryvkin, Edward Hemphill, Ion I. Mand...
RECOMB
2007
Springer
16 years 7 months ago
Support Vector Training of Protein Alignment Models
Abstract. Sequence to structure alignment is an important step in homology modeling of protein structures. Incorporation of features like secondary structure, solvent accessibility...
Chun-Nam John Yu, Thorsten Joachims, Ron Elber, Ja...
RECOMB
2007
Springer
16 years 7 months ago
Peptide Retention Time Prediction Yields Improved Tandem Mass Spectrum Identification for Diverse Chromatography Conditions
Most tandem mass spectrum identification algorithms use information only from the final spectrum, ignoring precursor information such as peptide retention time (RT). Efforts to exp...
Aaron A. Klammer, Xianhua Yi, Michael J. MacCoss, ...
RECOMB
2007
Springer
16 years 7 months ago
Design of Compact, Universal DNA Microarrays for Protein Binding Microarray Experiments
Our group has recently developed a compact, universal protein binding microarray (PBM) that can be used to determine the binding preferences of transcription factors (TFs) [1]. Thi...
Anthony A. Philippakis, Aaron M. Qureshi, Michael ...