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RECOMB
2008
Springer
16 years 7 months ago
Perfect DCJ Rearrangement
We study the problem of transforming a multichromosomal genome into another using Double-Cut-and-Join (DCJ) operations. We introduce the notion of DCJ scenario that does not break ...
Sèverine Bérard, Annie Chateau, Cedr...
RECOMB
2006
Springer
16 years 7 months ago
Inferring Positional Homologs with Common Intervals of Sequences
Inferring orthologous and paralogous genes is an important problem in whole genomes comparisons, both for functional or evolutionary studies. In this paper, we introduce a new appr...
Guillaume Blin, Annie Chateau, Cedric Chauve, Yann...
RECOMB
2006
Springer
16 years 7 months ago
Structural Alignment of Pseudoknotted RNA
In this paper, we address the problem of discovering novel non-coding RNA (ncRNA) using primary sequence, and secondary structure conservation, focusing on ncRNA families with pseu...
Banu Dost, Buhm Han, Shaojie Zhang, Vineet Bafna
RECOMB
2006
Springer
16 years 7 months ago
A Sublinear-Time Randomized Approximation Scheme for the Robinson-Foulds Metric
The Robinson-Foulds (RF) metric is the measure most widely used in comparing phylogenetic trees; it can be computed in linear time using Day's algorithm. When faced with the n...
Nicholas D. Pattengale, Bernard M. E. Moret
RECOMB
2006
Springer
16 years 7 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...