The prediction of the correct secondary structures of large RNAs is one of the unsolved challenges of computational molecular biology. Among the major obstacles is the fact that a...
Amrita Mathuriya, David A. Bader, Christine E. Hei...
We present a general, simple feature representation of sequences that allows efficient inexact matching, comparison and classification of sequential data. This approach, recently ...
Background: Expression array data are used to predict biological functions of uncharacterized genes by comparing their expression profiles to those of characterized genes. While b...
Molecular noise, which arises from the randomness of the discrete events in the cell, significantly influences fundamental biological processes. Discrete-state continuous-time st...
Knowledge of energy barriers between pairs of secondary structures for a given DNA or RNA molecule is useful, both in understanding RNA function in biological settings and in desig...