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SAC
2009
ACM
16 years 1 months ago
GTfold: a scalable multicore code for RNA secondary structure prediction
The prediction of the correct secondary structures of large RNAs is one of the unsolved challenges of computational molecular biology. Among the major obstacles is the fact that a...
Amrita Mathuriya, David A. Bader, Christine E. Hei...
ICPR
2010
IEEE
15 years 10 months ago
Spatial Representation for Efficient Sequence Classification
We present a general, simple feature representation of sequences that allows efficient inexact matching, comparison and classification of sequential data. This approach, recently ...
Pavel Kuksa, Vladimir Pavlovic
BMCBI
2006
120views more  BMCBI 2006»
15 years 6 months ago
A factor analysis model for functional genomics
Background: Expression array data are used to predict biological functions of uncharacterized genes by comparing their expression profiles to those of characterized genes. While b...
Rafal Kustra, Romy Shioda, Mu Zhu
CMSB
2009
Springer
16 years 1 months ago
Approximation of Event Probabilities in Noisy Cellular Processes
Molecular noise, which arises from the randomness of the discrete events in the cell, significantly influences fundamental biological processes. Discrete-state continuous-time st...
Frédéric Didier, Thomas A. Henzinger...
DNA
2009
Springer
185views Bioinformatics» more  DNA 2009»
16 years 1 months ago
NP-Completeness of the Direct Energy Barrier Problem without Pseudoknots
Knowledge of energy barriers between pairs of secondary structures for a given DNA or RNA molecule is useful, both in understanding RNA function in biological settings and in desig...
Ján Manuch, Chris Thachuk, Ladislav Stacho,...