Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
We present a new method for determining the consensus sequence in DNA fragment assemblies. The new method, Trace-Evidence, directly incorporates aligned ABI trace information into...
Carolyn F. Allex, Schuyler F. Baldwin, Jude W. Sha...
This workdemonstrates newtechniques developed for the prediction of protein folding class in the context of the most comprehensiveStructural Classification of Proteins (SCOP). The...
Protein chimerism is a phenomenon involving the combination of multiple ancestral sequences into a single, multi-domain protein through evolution. We propose a novel method for de...
Discrete motifsthat discriminate functionalclasses of proteins are useful for classifying newsequences, capturingstructural constraints, andidentifyingprotein subclasses.Despiteth...
Craig G. Nevill-Manning, Komal S. Sethi, Thomas D....