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175
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BMCBI
2006
15 years 6 months ago
2006
Background: As biology becomes an increasingly computational science, it is critical that we develop software tools that support not only bioinformaticians, but also bench biologi...
177
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BMCBI
2006
15 years 6 months ago
2006
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
180
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BMCBI
2006
15 years 6 months ago
2006
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
198
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BMCBI
2006
15 years 6 months ago
2006
Background: One-dimensional protein structures such as secondary structures or contact numbers are useful for three-dimensional structure prediction and helpful for intuitive unde...
164
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BMCBI
2006
15 years 6 months ago
2006
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...