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BMCBI
2006
90views more  BMCBI 2006»
15 years 6 months ago
A Fourier Transformation based Method to Mine Peptide Space for Antimicrobial Activity
Background: Naturally occurring antimicrobial peptides are currently being explored as potential candidate peptide drugs. Since antimicrobial peptides are part of the innate immun...
Vijayaraj Nagarajan, Navodit Kaushik, Beddhu Mural...
172
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BMCBI
2006
91views more  BMCBI 2006»
15 years 6 months ago
Cheminformatics methods for novel nanopore analysis of HIV DNA termini
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
Stephen Winters-Hilt, Matthew Landry, Mark Akeson,...
BMCBI
2006
157views more  BMCBI 2006»
15 years 6 months ago
Determination of the minimum number of microarray experiments for discovery of gene expression patterns
Background: One type of DNA microarray experiment is discovery of gene expression patterns for a cell line undergoing a biological process over a series of time points. Two import...
Fang-Xiang Wu, W. J. Zhang, Anthony J. Kusalik
172
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BMCBI
2006
114views more  BMCBI 2006»
15 years 6 months ago
Evaluation and comparison of mammalian subcellular localization prediction methods
Background: Determination of the subcellular location of a protein is essential to understanding its biochemical function. This information can provide insight into the function o...
Josefine Sprenger, J. Lynn Fink, Rohan D. Teasdale
182
Voted
BMCBI
2006
108views more  BMCBI 2006»
15 years 6 months ago
SPIDer: Saccharomyces protein-protein interaction database
Background: Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell,...
Xiaomei Wu, Lei Zhu, Jie Guo, Cong Fu, Hongjun Zho...
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